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Unravelling
health-to-disease
transitions

About us

The EU-funded research project IMMEDIATE strives to identify individual biomarkers of risk and resilience against chronic inflammation by investigating the diet-microbiome-metabolite-immune axis. This complex interaction refers to how an individual's diet, gut microbiota, metabolites, and immune system can influence their health.

IMMEDIATE will use cutting-edge technologies and clinical and metadata from large observational cohort studies to identify pre-disease stages and further our understanding of the mechanisms and molecular pathways underpinning non-communicable diseases. Furthermore, a proof-of-concept study on healthcare professionals will be conducted to test the effectiveness of a probiotic intervention and ultimately develop mobile apps designed to offer personalized lifestyle recommendations and empower citizens to manage their own health proactively.

IMMEDIATE video

01/01/2023 start date
48 months of duration
6.2 Mil € Budget
12 partners from 6 countries

Professor Dr med Friedemann Paul

Charité – Universitätsmedizin Berlin

As society and the environment change, we need novel prevention strategies for staying healthy. By expanding the overall understanding of chronic inflammation and health-to-disease transitions, we strive to provide citizens with personalised health guidance and innovative technological tools to reduce their risk of developing chronic diseases

Stay Healthy Cluster Symposium - Advancing Personalised Prevention to Support our Health

1–2 December 2025 | Berlin, Germany

The IMMEDIATE project, together with its sister Horizon Europe research initiatives forming the Stay Healthy Cl...

IMMEDIATE Launched a New Garmin Study on Stress and Resilience in Healthcare Workers

The upcoming observational study, developed in agreement with the IMMEDIATE Project Partners, aims to explore the potential of passive data collected...

IMMEDIATE Project Hackathon on Data Management

On 8–9 September, partners from Work Package 1 (FAIR Data Management and Integration for the AI Platform), led by the Max Delbrück Center (MDC) and...

Recruitment for the IMMEDIATE Proof-of-Concept Study Successfully Completed

The IMMEDIATE project has achieved a big milestone in our mission to explore the Gut-Brain-Microbiota Axis and the role of chronic inflammation in th...

Celebrating the World Microbiome Day 2025

This year’s World Microbiome Day theme is “Microbiome 101: What You Need to Know”, and it is all about making science easy to understand and empowerin...

Smartwatches in Clinical Research: A Valuable Opportunity

In this IMMEDIATE insight, Giulia Vismara, a Scientific Content Manager at Zadig srl writes about the opportunity smartwatches offer in clinical r...

First Stay Healthy Cluster Sharing Session held online

The first collaborative session within the Stay Healthy project cluster took place last Wednesday, marking an important step toward strengthening sy...

IMMEDIATE holds a successful 2nd Progress Meeting

The IMMEDIATE consortium gathered in Sczcezin, Poland, from the 19th to the 20th of March for the 2nd Progress Meeting, hosted by Pomeranian Medica...

IMMEDIATE and the SDGs: Climate change impacts on health

In this IMMEDIATE insight, Dr Sonja Bergner, an expert in sustainable innovation at EURICE, shares insights into how following a cross-cutting One...

Breaking Barriers: The Women behind IMMEDIATE

The path to a career in science is not always easy, especially for women. Despite progress, gender gaps in STEM remain, making it essential to celebra...

Mobile apps - how can they improve healthcare access and health outcomes?

IMMEDIATE Insight by Chiara Di Lucente

Mobile apps for digital health have emerged as game-changers in this field, letting people be more aware o...

Stay Healthy Cluster Projects Hold Their First Yearly Meeting

Last week, the Stay Healthy Cluster projects convened online for their first yearly meeting, hosted by the IMMEDIATE project and its coordinating te...

KTX360° study

In the next IMMEDIATE insight, Olena Potapenko and Johannes B. Holle from Charité dive deeper into the KTX360° study. The KTX360° study is a m...

Open position: Postdoctoral Research Associate in Mass Spectrometry – based Metabolomics

The Division of Systems Medicine at the IMPERIAL College London is looking for a Postdoctoral Research Associate in Mass Spectrometry – based Metabolo...

IMMEDIATE holds its second General Assembly Meeting

On the 27th of November, the IMMEDIATE consortium gathered virtually for their second General Assembly meeting. Around 25 members of the project att...

Biotechnology of the Future: Exploring New Horizons in Health and Innovation

On October 22nd, the Regional Centre for Innovation and Technology Transfer in Szczecin hosted the "Biotechnology of the Future: Development Paths ...

Inflammatory biomarkers in the health to disease transition: NAKO data contributes to IMMEDIATE project

After the list of observational cohorts used in the previous IMMEDIATE insights blog post, today we dive into the German National Cohort (NAKO). A...

Inflammation & health transitions – A population-level approach

In the following IMMEDIATE insights blog series, we will dive deeper into our observational cohorts. Solange Gonzalez Chiappe from the Max Delbrück...

Open position at Charité

Charité Berlin is looking for an Analytical Chemist /Metabolomics Expert to join their team working on the IMMEDIATE project.

They are looking...

IMMEDIATE SODAR DMP system

Dive deeper into the SODAR DMP system with Hong Li (Max Delbrück Center) in our latest IMMEDIATE insight blog.

To simplify the complexities of da...

IMMEDIATE Exploitation Strategy Workshop Milestone achieved

The partners from EURICE, who are responsible for the Innovation Management: Communication, Dissemination and Exploitation Activities within the IMM...

Celebrating World Microbiome Day: "Feed Your Microbes - How Diet Shapes Your Gut Microbiome"

June 27th marks World Microbiome Day, an international celebration aimed at raising awareness about the diverse community of microorganisms living w...

Proof of Concept study

Dive deeper into our proof-of-concept study with Karolina Skonieczna-Żydecka (Pomeranian Medical University in Szczecin) in our IMMEDIATE insight bl...

World Digestive Health Day

With World Digestive Health Day today, we raise awareness about the importance of prioritising digestive wellness under the theme: "Your Digestive Hea...

The transformative impact of digital health and mobile apps: enhancing efficiency in healthcare

In today’s IMMEDIATE insight, Chiara Di Lucente, a Scientific content manager at Zadig gives insights into health digitalization.

In recent years, t...

New IMMEDIATE video explains factors affecting our gut health

In a world full of health trends, it may be difficult to understand what contributes to our well-being. The EU-funded IMMEDIATE research project, is o...

IMMEDIATE Progress Meeting successfully held in Milan

The IMMEDIATE project, an innovative collaboration exploring the complex relationships between diet, the microbiome, metabolites, and the immune syste...

Open position at IMMEDIATE

Imperial College London is looking for a Research Associate to join their team working on the IMMEDIATE project.

They are looking for a Postdoctor...

What is multi-omics?

Let’s dive deeper into the world of multi-omics together with Jennifer Kirwan, Head of the Berlin Institute of Health Metabolomics Platform within C...

You are what you eat - is that true?

How do our diet and gut microbiome influence the immune system and the transition from health to disease?

Our deputy project coordinator, Chotima B...

International Day of Women and Girls in Science 2024

On 11 February, we celebrate the 9th International Day of Women and Girls in Science. This day is a reminder that women and girls play a crucial rol...

Data Management Workshop

The partners from Max Delbrück Center, who are responsible for the tasks related to FAIR data management and integration for the AI platform as part o...

IMMEDIATE General Assembly meeting

On the 29th of November, the IMMEDIATE consortium gathered virtually for their first General Assembly meeting. Kindly hosted by the project coordinato...

Join our clinical trial study

We are looking for medical professionals to participate in our clinical trial study. We are investigating the effect of a 3-month supplementation of A...

IMMEDIATE Kick-off Meeting Successfully Held in Berlin

The IMMEDIATE project, an innovative collaboration exploring the intricate relationship between diet, microbiome, metabolites, and the immune system,...

Workshop on the gut-brain connection at the 8th Long Night of Science

On 17 June 2023, the 8th Long Night of Science was held at the Max Delbrück Communications Centre in Berlin. Our Deputy Project Coordinator, Dr. Choti...

EU Knowledge Valorisation Week 2023: Learn More on Turning Research into Solutions

Join stakeholders and policymakers at the EU Knowledge Valorisation Week between 25 April and 28 April 2023. The annual event highlights best practice...

New Project “IMMEDIATE”

Launch of New EU Project “IMMEDIATE”: Unravelling Key Factors of Chronic Inflammation and Predicting Health-to-Disease Transitions

Led by Charité – ...